Відео

My Neurologist oof 30 years just retired but when I had an exacerbation he would send me for 3days of prednisone, I went to my new Neurologist and told him I was having an exacerbation dystonia, my whole body has jitters , no balance, severe fatigue, and the dystonia in my feet got so bad that my toes were twisted underneath, and my ankles were twisted in, and he told me that was not an exacerbation. It was just symptoms that I’ve had in the past he said an exacerbation is when you have, new symptoms not symptoms that you had in the past. I’ve had MS for 34 years I was group leader so I have followed up a lot on MS and I didn’t wanna argue with him, but is he right?

I was at 447 pg/mL and was having neurological issues. The level doesn’t necessarily dictate the symptoms. Mental symptoms of this are terrible. Many physical issues too.

O.K. I'm 57, diagnosed at 55 with PPMS. Doctor set me up on Ocrevus. I declined! Told her I need a second opinion. Was not happy with her treatment, so not confident in her prescription of Ocrevus. Just stuck with her because I thought switching doctors might mess up my disability claim. Looking for new doctor for that 2nd opinion. Plus having PPMS, the best Ocrevus is going to do is maybe keep me out of a wheelchair in the next 5 to 10 years. The more I watch stuff like this I see no benefit for PPMS. So, still going to stay off everything for now.

the abdominal trunk banding[hug] pain associated with TM: current dose 100mg not helping so my Neuro doctor upped the dose 2 or 3 times a day. will see if that works.

Good video looking at the evidence. The longer I read up on long-term cohort and controlled studies related to diet and how they relate to longevity, the more I am convinced the more plants you eat and the fewer animal products you consume, the better off you'll be. It seems like regularly more and more evidence comes out showing a positive for a plant-based diet as it relates to specific diseases and I welcome what future research brings. Another benefit, or more so the primary benefit is that by going vegan in addition to a plant-based diet, we no longer violate the rights of others and can live a happy and healthy life. Be well!

Doctor plz my baby has optic neuritis problem is there any treatment plz give me phn no.

Can you please explain on your next video the difference between Spastic paraplegia/ms/ataxia ? Thanks

I have gluten ataxia and i was treated with Gabapentin and Tramadol. Worse experience ever..... Mow i take Xanax 0,5 and I am way better.

I'm on Betaseron since 2010. Should I switch to KESIMPTA B-cell treatment or Any Multiple Sclerosis Pill you recommend?

Anyone tried KESIMPTA or Any Multiple Sclerosis Pill you recommend?

More original thought. Doing my own research. Consider: We know many biological organisms, often tend to be predatory in both nature and behavior. Some often use a myriad of methods to avoid detection; even taking over the host themselves. Then: it is clear, Many remain well hidden, until they reach a state where they are ready to reproduce. It follows, it might be possible, the invading organisms hide within whatever cells which cause MS, and needing simple lipids, well known to sheath the meyelin in the body, because nerves tend to be slow, or do not regenerate, this is likely why the onset of MS often increases slowly over time, and because simple research suggests action, typical of microscopic and hungry organisms, hiding and well undetected by ordinary exam, it follows, medication and products we all now know are being used today to abate further damage to the meyelin sheath, it becomes increasingly clear, Medical Personnel are CLEARLY AWARE of the cause for the destruction of the meyelin sheath in MS. Here, as I looked for both correlation and causation, the conclusions I reached, all led to some medical product,. Called Kesimptra and Rebagio. Hmmm.. 🤔 See below what my conclusions led to:   Filters and Topics All Images Shopping News Videos Forums Maps Web Books Flights Finance Search tools Feedback Ads Sponsored  quickrxspecialty.pharmacy quickrxspecialty.pharmacy/aubagio-copay/assistance Teriflunomide Copay Assistance - Quickrx Pharmacy  Dedicated Copay Assistance Programs For Aubagio With Personalized Support. Contact Us Call (917) 830-2525 Sponsored vumerityhcp.com www.vumerityhcp.com/ VUMERITY® (diroximel fumarate) - Resources for Prescribers  Support Your Patient's Journey With Valuable Insights And Treatment Info From Physicians. GI Tolerability Info VUMERITY® Efficacy Coverage & Access Info E-Sign Start Form Switching to VUMERITY® Getting Started Support For Your Patients Learning Tools for HCPs Sponsored vumerity.com www.vumerity.com/ VUMERITY® (diroximel fumarate) - Adherence & Dosing  See What VUMERITY® Could Do For You. Explore More Information On The Patient Site. Sponsored kesimptahcp.com www.kesimptahcp.com/learn-more KESIMPTA® (ofatumumab) - Learn About KESIMPTA®  View KESIMPTA® Full Prescribing Information. FDA-Approved Treatment Option From Novartis. Search Results Teriflunomide Overview Function Main Results Teriflunomide, sold under the brand name Aubagio, is the active metabolite of leflunomide. Teriflunomide was investigated in the Phase III clinical trial TEMSO as a medication for multiple sclerosis. The study was completed in July 2010. 2-year results were positive. ... Wikipedia Price around $275 for a supply of 30 tablets  drugs.com Release date March 13, 2023  professionals.optumrx.com Efficacy…how effective is teriflunomide Brand name…Teriflunomide brand name Generic name…what is the generic name for aubagio Benefits…teriflunomide benefits 6 more Feedback People also ask What is the drug teriflunomide used for? What does teriflunomide inhibit? Is teriflunomide an Immunosuppressant? What does Aubagio do to your body? This medication is used by adults to treat multiple sclerosis-MS. It is not a cure for MS but is thought to work by decreasing certain immune system cells (lymphocytes) which can attack the nerves in your brain and spinal cord.  www.webmd.com › details Aubagio Oral: Uses, Side Effects, Interactions, Pictures, Warnings ... MORE RESULTS Do you gain weight with Aubagio? Is teriflunomide a DMT? Who should not take Aubagio? Can Aubagio make MS worse? Does Aubagio cause hair loss? Does teriflunomide make you tired? How much does Aubagio cost per month? What time of day should I take Aubagio? Can you drink alcohol with Aubagio? Can you just stop taking Aubagio? Is Aubagio better than Ocrevus? What are the long-term effects of Aubagio? What foods to avoid if you have multiple sclerosis? Can I take Aubagio every other day?  Mayo Clinic www.mayoclinic.org › drg-... Teriflunomide (Oral Route) Description and Brand Names Teriflunomide is used to treat the relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active ... About AHFS/Drugs.com: Monograph ATC code: L04AK02 (WHO) Elimination half-life: 2 weeks Other names: A77 1726 Pregnancy category: : AU: X (High risk); Contraindicated; Protein binding: >99.3% Trade names: Aubagio Feedback  National Institutes of Health (NIH) (.gov) www.ncbi.nlm.nih.gov Teriflunomide - PMC by J Oh · 2013 · Cited by 26 - Teriflunomide is a novel disease-modifying agent that was recently approved for use in the treatment of multiple sclerosis (MS).  WebMD www.webmd.com › details Teriflunomide Oral: Uses, Side Effects, Interactions, Pictures, ... This medication is used by adults to treat multiple sclerosis-MS. It is not a cure for MS but is thought to work by decreasing certain immune system cells ...  Cleveland Clinic my.clevelandclinic.org › 18... Teriflunomide Tablets: Uses & Side Effects Teriflunomide is a medication that decreases the number of flare-ups caused by multiple sclerosis. MS affects your central nervous system.  Wikipedia en.wikipedia.org › wiki › T... Teriflunomide Teriflunomide, sold under the brand name Aubagio, is the active metabolite of leflunomide. Teriflunomide was investigated in the Phase III clinical trial ...   MedlinePlus (.gov) medlineplus.gov › meds Teriflunomide: MedlinePlus Drug Information Jan 15, 2021 - Teriflunomide: learn about side effects, dosage, special precautions, and more on MedlinePlus.  Medscape reference.medscape.com › au... Aubagio (teriflunomide) dosing, indications, interactions, adverse ... USES: This medication is used by adults to treat multiple sclerosis-MS. It is not a cure for MS but is thought to work by decreasing certain immune system cells ...  Mayo Clinic www.mayoclinic.org › drg-... Teriflunomide (Oral Route) Precautions Teriflunomide can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. It can also lower the number ...  National Institutes of Health (NIH) (.gov) www.ncbi.nlm.nih.gov Teriflunomide in the treatment of multiple sclerosis: current ... by J Oh · 2014 · Cited by 63 - Teriflunomide has demonstrated efficacy and safety in a number of phase III trials in the treatment of relapsing MS, both as monotherapy or as an add-on agent.  DrugBank go.drugbank.com › drugs Teriflunomide: Uses, Interactions, Mechanism of Action - DrugBank May 20, 2013 - Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is ... Identification Pharmacology Interactions Products Categories Chemical Identifiers References People also search for Teriflunomide mechanism of action Teriflunomide side effects Teriflunomide brand Page Navigation

In all videos it is said, that dmts are most helpful, when one only begins to have ms. But how to know, if you only started to have it? So I’ve been diagnosed 3 months ago and already had more than 50 lesions, and they all mixed together, so that it’s impossible to count them. So it seems like I have ms for several years already. Does it mean that I missed the time and I will soon get disabled? I’m so scared I want to be healthy until at least I’m 40. I’m 24 right now

My very unscientific study just seeing a whole slew of very old to a few newer videos made by peoples "My MS Story" ,gives me the impression that for a lot if them, long term use hasn't made much difference. It's a progressive, wildly erratic targeting illness. The side effects alone for a few I tried, left me with no desire to live with these. My worst symptoms thankfully have been just severe spastic muscles and 24/7 pain which I have just learned to live with. Medicines designed for Ms at least for me make that even harder.🤔

Great analysis. It will be great to see long term data on these stronger DMT’s! Hopeful for sure. My 1st symptom was tingling in my foot & saw a neurologist quickly to refer me to a MS specialist . I do believe early intervention may make a difference.

THANK YOU DOCTOR

When my symptoms began, my Vitamin D level was extremely low at just 7. 😮

Fascinating! Thank you for this. So much to think about. I’m 49, dx at 33, one flare that got me my diagnosis, and on Kesimpta now which I love. I do notice my existing symptoms getting worse with time- particularly heat intolerance, fatigue, musculoskeletal pain, and paresthesia. I’ve been thinking a lot lately about how to possibly tease apart what is MS, what is perimenopause, weight gain, and what is just aging. This just gives me more to think about! Very interesting. Thank you!

I was diagnosed when I was 33 years old (

Information- Boom 💥 I like it

I just got a cervicle mri and saw lots of tiny white dots. I’m terrified and now have to wake a week for results

Dr my son of 2 years was injected wrongly on the buttocks last week and this has caused him foot drop. What do I do? Please i need help

I've heard and seen so many nightmares about this drug. They hand it out like candy. Unbelievably irresponsible. First, make billions. Then do no harm may be second...or fifth.

Gabapentin helped me enormously with the side effects of withdrawal from benzodiazepines after five years of awful struggle and failed withdrawals. It wiped out all the physical symptoms (and they are hellish) and helped with the anxiety too. I tapered off the benzos in about 30 days, and then the Gabapentin after about six months. Everything was fine. It can be a great drug, if used in the right circumstances.

I was on that drug for 6 years Horrible 👎

I failed both copaxone and Rebif in the years after my diagnosis. The side effects were absolutely horrible. I don’t know why these drugs are even being offered anymore, considering that we now have highly effective therapies (Tysabri , Ocrevus, etc.). Why are insurance companies allowed to force people to take it, when it has such a low efficacy profile? In my opinion they should not be on the market anymore. The damage that happened while I was on them is irreversible and inexcusable. I went from working full time as an RN to being on disability permanently. Please, if you are prescribed interferons, ask your neurologist to fight the insurance company for a medication that will actually make a difference.

the fact that it works is actually worrying because it implies that it's having a great effect on your body, which means side-effects and withdrawal symptoms that need to be studied

I take 100mg at night because 300 made me feel like i’m in a fish bowl. It doesn’t seem to do much for my pain but I do see a noticeable difference in my anxiety levels. I keep taking it for that reason.

Do better research. Low carb is the key.

Hi Doctor, how can I make an appointment with you if I am not in the US?

As far as I can tell ALL MS is progressive. Difference is only symptomatic.🤔

3600 MG for trigemsinal neuralgia. Super l

7:42 When you talk about how everything online was negative... god damn i can relate to that. There is so much depressing stuff and also just straight up overly positive BS... it's hard to find accurate information about MS online. Makes me so angry

I took 300mg 3x/day for numbness and tingling in my hands and feet from MS. I didn't notice any real improvement in those symptoms. I did feel dizziness and drowsiness side effects. Ultimately I made the choice to stop taking gabapentin, as I wasn't having enough benefit to mitigate the negative impact.

This is a miracle drug.. I'm in limbo have had a nuero cough ands extreme muscle spasms .. this med gave me my voice and life back. Can def tell if i miss a few days!! Helps with pain that no muscle relaxers or opiates have!!

My neurologist prescribed Pregabalin 500 mg three times a day for nerve pain. I found it causing more pain, and felt more uncomfortable while using those pills. I cut them off completely, and the pain subsided massively. I rather stretch and lift some weights to control the nerve pain in my leg and arm, as this medication didn’t help me much.

Thank you going over the topic! I was quite surprised to see how high the therapeutic dose ranges were for gabapentin and pregabalin. Are you aware of any predisposing factors that contribute to side effect profile? Particularly in terms of the cognitive impairments? (e.g. confusion, memory problems, drunkenness feeling) I (32 year old white male, 200cm and 124 kg) am currently trying to figure out a sustainable treatment regiment for pain related to bilateral L5 radiculopathy and an idiopathic peripheral polyneuropathy / small fiber neuropathy. I was unable to tolerate either medication; gabapentin was too impairing at 100mg BID and pregabalin at 75 mg BID. I am unfortunately very prone to somnolence as well; this was the main reason I could not tolerate Effexor or Cymbalta when I had tried them for depression in the past (along with SSRIs). This rules out the tricyclics as well. Would you be able to speak to the use of tapentadol in nerve pain? That has been the only effective measure for me currently, albeit an unsustainable one. Its FDA indication for diabetic neuropathy seems to me to put it in the same sphere as gabapentin (though only the later is indicated for shingles). I found it strange that the physicians I have seen (across various disciplines) did not seem to be aware of it prior to my asking about it. Is it simply a case of it being shunned for being an opioid? Or perhaps below average marketing efforts to doctors via their pharma reps? That had concerning implications that other patients may not be presented this option since they don't have the knowledge or access to journal articles to evaluate evidence for alternate treatments and present it to their doctors like I was fortunate enough to be able to.

Its pretty amazing what that lone benzene ring can change. Is the gaba+ benzene compound found any where else in the body ? Once ( and if). the medication loses the benzene it has a completly different effect.

Big respect for the caveat makes your analysis seem much more reliable! Excellent work

Is Maalox the only anti acid to avoid within 2hrs? What about Tums (calcium carbonate)? I have bad nausea and I’m also on up to 6 Zofran a day. I take it more days than not. I was just prescribed fematidine

I was offered this for my dog, I refused as I was familiar with this drug.

You have to taper off this drug. It’s dangerous.

Gabapentin caused my Mom to lose her marbles for about a week. I took her to another doctor and got her off all her meds and only added back the ones she needed. It wasn't even helping her with the pain.

I take 1200mg of gabapentin daily for muscle tightness (spasticity). The effect is mild, but very obvious if I miss a dose. None of the traditional muscle relaxants work for me.

I take 200mg at night before I go to bed. I have ms. I was having horrible headaches. This really helped me with those but it also helped me with my seizures as well (this was something we didnt even anticipate happening). I take another medication for seizures as well. I don't have side effects from the gabapentine.

I have MS for 18 years. I was experiencing terrible back pain and spasms and was recently given Gabapentin for help get me through an EMG. I will NEVER take that medication again. I could barely answer questions from the medical staff. I felt like my brain was under water and could not think clearly. Both of the technicians who conducted the EMG thought that I had been prescribed way too much. That may have been the case. But in fairness to my neurologist, I seldom take any medications, so maybe I've overly sensitive. The only prescription medications I take are Synthroid and Tysabri. I worry that if I were to be prescribed Gabapentin for daily use, I'd be housebound.

Thanks for sharing this info. I've been lucky enough to not have issues with MS nerve pain. However, Gabapentin helped my childhood dog tremendously with her severe arthritis. My wife's cousin is a vet tech and uses it to treat her dog's arthritic spinal issues as well.

I take it for oscillopscia.. i can't go over 300mg morning and night. I daren't take more, it ruins my mood

I take 300mg in the morning and at night. I used to get severe stabbing pains in my spine right around where my spinal lesion is. I was prescribed gabapentin after an emergency visit and didnt know it was a long term medication. I stopped taking it after 3 months and the stabbing pain came back. My family doctor now has me on it consistently and the stabbing pain is almost completely gone. Occassionally I will get a sharp tinge but it goes away quickly.

Great video! I was first prescribed gabapentin for restless leg. I don’t think I gave it a chance as I only took it for a couple weeks and it didn’t help. Then I had shingles last fall and was prescribed it for pain. Not sure if they gave me a high enough dose because it didn’t seem to help. My MS causes extreme foot sensitivity..I have to wear socks all the time or my feet jerk every time they touch a surface. Pedicures are torture. I’ve heard this extreme foot sensitivity is a type of neuropathic pain. Is that true? Have you had patients that suffer from this and do you think this is something gabapentin could help with? If not is there something else that might help? Thanks

gabapentin is no better than fentanyl.. and just as easy to sell on the street have you taken either of these drugs????